Buy 1P LSD Blotter Online

Description

Buy 1P LSD Blotter Online

Buy 1P LSD Blotter or 1-propionyl-lysergic acid diethylamide is a psychedelic drug of the lysergamide class that is a derivative and functional analogue of LSD and a homologue of ALD-52. It has been sold online as a designer drug since 2015. It modifies the LSD molecule by adding a propionyl group to the nitrogen molecule of LSD’s indole.

The original synthesis date of 1P LSD  is not known. Reports of  LSD Blotter  use first surfaced in 2015 subsequent to its appearance on the online research chemical market. It was marketed as a legal alternative to LSD alongside novel lysergamides like ALD-52, ETH-LAD and AL-LAD.

Pharmacology

In mice, 1P-LSD produces LSD-like effects with 38% the potency of LSD and it is therefore classed as a serotonergic hallucinogen. However, 1P-LSD itself is unable to bind to the serotenergic 5-HT2A receptors. But since LSD is detected when 1P-LSD is incubated in human serum, 1P-LSD may act, at least in part, as a prodrug for LSD.

History and culture

1P LSD  first appeared on the online research chemical market in January 2015. Although it was likely discovered in an academic setting, it is unknown who first synthesized 1P-LSD, as the substance does not appear in any academic literature pre-dating its arrival on the research chemical market. Interestingly, the future usage of 1-akylated lysergamide derivatives as a means to bypass controlled substance laws banning LSD as a precursor was foreseen in a DEA report from 1988:
“ …a reduction in hallucinogenic activity may become acceptable to the U.S. clandestine chemist when he notes that lysergic acid amide is listed as a Schedule III substance in the CFR; therefore, structurally similar substances of this compound are exempted from the CsA amendment. A lucid argument can then be made that lysergic acid N,N-dimethylamide is derived from lysergic acid amide rather than LSD. Carrying this theme to the next logical step one would then assume that the 1-alkyl and 1-acyl derivatives of the N,N-dimethyl isomer would also not be controlled by the CsA amendment.